Preterm Premat�r Membran R�pt�r�nde Serebroplasental Oran ve Perinatal Sonu�lar

Ayas �zkan, Merve; �zkan, Halis Do�ukan; Tolunay, Harun Egemen; Yucel, Aykan

Cilt : 36 Say� : 2 Y�l : 2025

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Preterm Premat�r Membran R�pt�r�nde Serebroplasental Oran ve Perinatal Sonu�lar [South Clin Ist Euras]

South Clin Ist Euras. 2025; 36(2): 177-182 | DOI: 10.14744/scie.2025.79989

Preterm Premat�r Membran R�pt�r�nde Serebroplasental Oran ve Perinatal Sonu�lar

Merve Ayas �zkan¹, Halis Do�ukan �zkan², Harun Egemen Tolunay¹, Aykan Yucel³
¹
²
³

G�R�� ve AMA�: Erken membran r�pt�r� (PPROM) olan gebelerde serebroplasental oran (CPR) ile k�t� perinatal sonu�lar aras�ndaki ili�kiyi kar��la�t�rmak.
Y�NTEM ve GERE�LER: Bu prospektif g�zlemsel �al��ma, gebelik haftas� 24-36 aras�nda, tekil gebeli�i olan ve PPROM tan�s� alan hamile kad�nlar� i�ermektedir. CPR iki grupta (<1 ve >1) analiz edilmi�tir. Do�um endikasyonu, do�um y�ntemi, do�um a��rl�� ve k�t� perinatal sonu�lar kaydedilmi�tir. Fetal distres, do�um karar�n�n belirleyicilerinden biri olarak kullan�lm��t�r. Fetal distres, ACOG k�lavuzuna g�re kategori 3 fetal kalp at�m h�z� izlemesi olanlar olarak kabul edilmi�tir.
BULGULAR: Fetal distres, CPR <1 grubunda CPR >1 grubuna g�re anlaml� olarak daha y�ksekti (28.6�ya kar�� %6.9, p=0.006). D��k ve y�ksek CPR gruplar� aras�nda do�um a��rl�� (2140�485.7 ve 2225�470.1, p=0.390) ve 5. dakika APGAR skorlar� (9 ve 10, p=0.159) a��s�ndan anlaml� bir fark g�zlenmedi. Yenido�an yo�un bak�m ihtiyac� iki grup aras�nda benzerdi (%40 ve %30, p=0.332).
TARTI�MA ve SONU�: PPROM�da d��k CPR, fetal distres ile ili�kilidir. Klinisyenler, PPROM gebeliklerinin takibi s�ras�nda fetal durumu belirlerken CPR kullan�m�n� de�erlendirebilirler.

Anahtar Kelimeler: Doppler ultrason, erken membran r�pt�r�, perinatal sonu�lar, serebroplasental oran.

Cerebroplacental Ratio and Perinatal Outcomes in Preterm Premature Rupture of Membranes

Merve Ayas �zkan¹, Halis Do�ukan �zkan², Harun Egemen Tolunay¹, Aykan Yucel³
¹Department of Perinatology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, T�rkiye
²Department of Obstetrics and Gynecology, L�sante Child and Adult Hospital, Ankara, T�rkiye
³Department of Perinatology, University of Health Sciences, Ankara City Hospital, Ankara, T�rkiye

INTRODUCTION: The aim of this study is to compare the relationship between cerebroplacental ratio (CPR) and adverse perinatal outcomes in pregnant women with preterm premature rupture of membranes (PPROM).
METHODS: This prospective observational study included pregnant women who were at 24−36 weeks� gestation, had a singleton pregnancy and were diagnosed with PPROM. CPR were analysed in two groups (<1 and >1). Birth indication, delivery method, birth weight and poor perinatal outcomes were recorded. Foetal compromise was used as one of the determinants of the labour decision. Foetal compromise was diagnosed in those with category 3 foetal heart rate trace based on the ACOG guideline.
RESULTS: Fetal compromise was significantly higher in the CPR of <1 group than in the CPR of >1 group (28.6 vs. 6.9%, p=0.006). No significant difference was observed between the low and high CPR groups in terms of birth weight (2140�485.7 vs. 2225�470.1, p=0.390) and 5th min APGAR scores (9 vs. 10, p=0.159). Neonatal intensive care needs were comparable between the two groups (40% vs. 30%, p=0.332).
DISCUSSION AND CONCLUSION: Low CPR in PPROM is associated with foetal compromise. Clinicians might consider to use CPR in determining the foetal status during follow-up of a PPROM pregnancy.

Keywords: Cerebroplacental ratio, doppler diagnostic, perinatal outcomes, premature rupture of membrane.

Sorumlu Yazar: Merve Ayas �zkan, T�rkiye
Makale Dili: �ngilizce

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