DÝYABET SÜRESÝ, HBA1C DÜZEYLERÝ VE RETÝNOPATÝ

Bu çalýþmada diabetli hastalarda diabetin mikrovaskuler komplikasyonlarmdan olan retinopati ile HbA1c, arasýndaki iliþkiyi ve HbA1c düzeyinin izlenmesinin, diabetin mikrovaskuler komplikasyonlarýnýn ortaya çýkmasýný önlemekte ve tedaviyi yönlendirmekteki rolü araþtýrýlmýþtýr. Hastanemiz diabet polikliniðine 1997-98 yýllarý arasýnda baþvuran, en az 5 yýllýk Týp 2 DM öyküsü olan 62'si kadýn, 22 'si erkek 84 hasta deðerlendirildi. Hastalarýn yaþlarý, cinsiyetleri, HbA1c düzeyleri, diabet süreleri, tedavi tipleri ve göz dibi bulgularý saptandý. Fundus incelemesi normal olan 54 olgunun ortalama HbA1c düzeyi %7,8 iken, retinopati saptanan olgularda bu oran %10'du (p<0,05). Olgularýmýz diabet süreleri açýsýndan deðerlendirildiðinde HbA1c düzeyleri arasýnda istatistiksel olarak anlamlý fark bulunmadý (p>0,05). Çalýþmanýn sonuçlan HbA1c'nin diabet süresi ile iliþkili olmadýðýný, retinopati gözlenen olgularda daha yüksek olduðunu, retinopatinin ise hem HbA1c düzeyi, hem de diabetin süresi ile pozitif iliþkili olduðunu göstermektedir.

DURATION OF DIABETES, HBA1C LEVELS AND RETINOPATHY

In this study, the correlation between HbA1c and retinopathy, one of the microvascular complications of diabetes mellitus; and the effects of HbA1c levels on protection from complications and its effects on treatment were investigated. 84 patients (F/M=62/22) who were admitted to outpatient clinic of diabetes between 1997-1998 and have Type 2 DM for at least 5 years, were evaluated. Age, gender, HbA1c levels, diabetes duration, treatment method and fundus examination of each patient were detected. Mean HbA1c levels of 54 patients whose fundus examination were normal was 7,8%; on the other hand among patients who had retinopathy it was 10% (p< 0,05). There was no statistically significant difference between HbA1c levels when compared according to diabetes duration (p> 0,05). As a result, we found that there was no relation between HbA1c and diabetes duration, HbA1c levels were higher among patients with retinopathy and there was a correlation between retinopathy and both HbA1c levels and diabetes duration.