Retroperitoneal Dev Mikst Adenöroendokrin Karsinom: Olgu Sunumu

Apendiks mukoselinin en yaygýn ikinci görülme þekli musinöz kistadenokarsinomdur. Sað retroperitoneal boþluðun tamamýna yakýný dolduran nadir görülen miks adenöroendokrin karsinom (MANEC) olgusu sunulmaktadýr. Altmýþ dört yaþýnda erkek hasta; sað alt kadranda palpabl kitlesi mevcuttu. Bilgisarlý batýn tomografisinde (BBT) 31x25x25 cm boyutlarýna ulaþan multisepatalý kistik kitle görülmüþtür. Literatürde 50 olgu rapor edilmiþ olup; büyük ve dev mukosellerin ortalama çaplarý 13 ile 40 cm arasýnda deðiþmesine raðmen bu olgularýn sadece bir kaçýnda müsinöz kistadenokarsinom rapor edilmiþtir. Operasyonda; kistadenom ya da hiperplazide apendektomi yeterli tedavi olarak görülse de kistadenokarsinomda sað hemikolektomi yapýlmalýdýr. Bu olgumuz patolojik tanýsý mikst adenonöroendokrin karsinom (nöroendokrin karsinom/adenokarsinom oraný 30/70) olmasý dolayýsyla literatürde tek olgudur.

Retroperitoneal Giant Mixed Adenoneuroendocrine Carcinoma: Case Report

Mucinous cystadenocarcinoma remains the second most frequent cause of appendiceal mucocele. Presently described is a case of mixed adenoneuroendocrine carcinoma (MANEC) located in the right retroperitoneal space. A 64-year-old male was admitted with a palpable mass in the right lower quadrant. An abdominal computed tomography scan revealed a cystic mass in the pelvic area 31x25x25 cm in size. A search of the literature yielded more than 50 similar cases, with mean diameter of 13 to 40 cm; however, only a few of these cases were mucinous cystadenocarcinoma. Usually, an appendectomy is sufficient therapy for cystadenoma and hyperplasia, while a right hemicolectomy is required for cystadenocarcinoma. To our knowledge, the present case is the first with a pathological diagnosis of MANEC (30/70 neuroendocrine carcinoma and adenocarcinoma) to be reported.