Dislipidemide Ceviz veya Ceviz Suyunun Yeri

GÝRÝÞ ve AMAÇ: Bu çalýþmada dislipidemi tedavisinde ceviz, ceviz suyu kürleri ve diyetin etkilerinin karþýlaþtýrýlmasý amaçlandý.
YÖNTEM ve GEREÇLER: Hastanemize baþvuran, dislipidemisi olan 90 hasta araþtýrmamýza alýndý. Rastgele 30’arlý üç grup oluþturuldu. Alýþýlmýþ diyete ek olarak, birinci gruba her sabah 30 gram ceviz yemeleri, ikinci gruba her sabah 30 gr ceviz suyu içmeleri ve üçüncü gruba dislipidemi diyeti önerildi. Dört hafta sonra lipid parametreleri kontrol edildi.
BULGULAR: %55.6’sý kadýn %44.4’ü erkek olan hastalarýn ortalama yaþý 49.1±13.3 idi. Ceviz kürü verilen grubun çalýþma baþýnda alýnan ilk lipid düzeyleri sýrasýyla total kolesterol: 246±39.8 mg/dl, LDL-k: 131.8±30.9 mg/dl, HDL: 44.3±14.7 mg/dl, TG: 147±99.1 olarak bulundu. Dört hafta sonra alýnan kontrol düzeyleri; T-chol: 242±34.4 mg/dl, LDL-k: 134.7±28.2 mg/dl, HDL: 41.5±16.1 mg/dl, TG: 154±78.9 mg/dl idi. Aradaki fark istatistiksel olarak anlamlý deðildi (p>0.05). Ceviz suyu içen grubun ilk bakýlan lipid düzeyleri; T-chol: 251.3±35.5 mg/dl, LDL-k: 129.9±32.3 mg/dl, HDL: 41.8±13.7 mg/dl, TG: 167±74.4 mg/dl olarak bulundu. Kontrol deðerler; T-chol: 248±36.1 mg/dl, LDL: 125.3±31.9 mg/dl, HDL: 42.9±14 mg/dl, TG: 174±68.7mg/dl olup aradaki fark istatistiksel olarak anlamlý deðildi (p>0.05). Sadece diyet önerdiðimiz grubun ilk bakýlan lipid düzeyleri; T-chol: 255.4±35.1mg/dl, LDL-k: 142.5±33.7 mg/dl, HDL: 43.8±17.3 mg/dl, TG: 158.8±79.6 mg/dl olup, kontrol deðerler; T-chol: 231.5±25.6 mg/dl, LDL-k: 119±28.1 mg/dl, HDL: 44.1±15.2 mg/dl, TG: 140.5±63.4 mg/dl olup aradaki fark istatistiksel olarak anlamlý bulundu (p<0.05).
TARTIÞMA ve SONUÇ: Cevizin dislipidemide tedavi amaçlý kullanýmý yönünde bir sonuca varmak için daha geniþ kapsamlý çalýþmalara ihtiyaç vardýr. Dislipidemik hastalara diyetin önemini vurgulamanýn halen en geçerli tedavi yöntemi olduðu düþüncesindeyiz.

Effect of Walnut or its Juice on Dyslipidemia

INTRODUCTION: The aim of the present study was to evaluate the effects of walnut, walnut juice, and diet on dyslipidemia.
METHODS: A total of 90 patients with dyslipidemia who applied to our hospital were included and randomly divided into 3 groups. In addition to routine diet, 30 grams of walnut were administered each morning to the 1st group, 30 grams of walnut juice were administered to the 2nd group and a diet tailored for dyslipidemia was administered to the 3rd group. Lipid parameters were checked after 4 weeks.
RESULTS: Mean age of patients, 55.6% of whom were female and 44.4% of whom were male, was 49.1±13.3 years. The first lipid levels of the first group were: total cholesterol (T-chol) 246±39.8 mg/dL, low-density lipoprotein (LDL) 131.8±30.9 mg/dL, high-density lipoprotein (HDL) 44.3±14.7 mg/dL, and triglycerides (TG) 147±99.1. After 4 weeks, control levels were: T-chol 242±34.4 mg/dL, LDL 134.7±28.2 mg/dL, HDL 41.5±16.1 mg/dL, and TG 154±78.9 mg/dL. Difference was not statistically significant (p>0.05). Lipid levels of the 2nd group were: T-chol 251.3±35.5 mg/dL, LDL 129.9±32.3 mg/dL, HDL 41.8±13.7 mg/dL, and TG 167±74.4 mg/dL. Control levels were T-chol 248±36.1 mg/dL, LDL 125.3±31.9 mg/dL, HDL 42.9±14 mg/dL, and TG 174±68.7 mg/dL. Difference was not statistically significant (p>0.05). Lipid levels of the group to which the diet was administered were: T-chol 255.4±35.1 mg/dL, LDL 142.5±33.7 mg/dL, HDL 43.8±17.3 mg/dL, and TG 158.8±79.6 mg/dL. Control levels were: T-chol 231.5±25.6 mg/dL, LDL 119±28.1 mg/dL, HDL 44.1±15.2 mg/dL, and TG 140.5±63.4 mg/dL. Difference was statistically significant (p>0.05).
DISCUSSION AND CONCLUSION: More extensive studies are needed to judge the suitability of walnut in treating dyslipidemia. Results demonstrate that diet is still the best treatment.