OBJECTIVE: The aim of this study was to investigate the hemostatic effect of Ankaferd Blood Stopper (ABS) on salivary gland tissue.
METHODS: Fifteen adult Wistar Albino rats were used in this study. After an appropriate dissection, the right submandibular glands were incised through all layers and 0.2 cc of ABS was
administered. After performing the same procedure on the left glands, compression was applied with a saline-moistened pack. The duration of bleeding on both sides was measured.
RESULTS: The duration of bleeding was 21.9±8.9 seconds in the ABS administered side, whereas the duration of bleeding was found to be 89.8±33.9 seconds in the side in which only a salinemoistened pack was applied. The duration of bleeding was significantly shorter in the ABS administered side.
CONCLUSION: ABS as a novel hemostatic agent could have a potential benefit in controlling bleeding from salivary glands. Further prospective controlled studies are required to investigate
its pathological effects on the tissue and to determine possible toxic effects.

OBJECTIVE: In this study, we aimed to make analysis of patients in whom lower gastrointestinal system stomas were performed at General Surgery Clinic of Istanbul Bakirkoy Dr. Sadi
Konuk Training and Research Hospital during last six years.
METHODS: Totally 201 patients in whom stoma was performed following emergency or elective lower gastrointestinal system surgery during May 2005 and May 2011 were retrospectively analyzed. Indication, stoma type, surgical complications of stoma,
time to stoma closure and complications related to closure were evaluated.
RESULTS: Of the 201 patients, 60% were male. Mean age of the patients were 70.5 (range 18 to 87 years). Stomas were performed via emergency surgery in 82,5% of cases. Surgery for recto-sigmoid cancer was the leading indication (52%). End colostomy was preferred in 27% of the patients. Overall complication rate of 10% was observed related to stoma (stenosis, ischemia, prolapsus, parastromal hernia and retraction). The highest complication rate was in patients with end colostomy. Totally 43% of the stomas could not be closed due to several reasons where death before closure was the major cause (53%). A complication rate of 30% was observed in cases when stoma closure was performed. The most common complication which is wound infection was observed in end colostomy closure. The lowest overall complication rate was in group of loop enterostomy patients.
CONCLUSION: Stoma is a surgical procedure which has a relatively high complication rate. For this reason in lower gastrointestinal tract surgery, primary anastomosis should be the first
choice in general. In cases where stoma is needed, loop enterostomy should be preferred, when possible.

OBJECTIVE: The aim of our study was to evaluate depression and burnout levels and their relation with sociodemographic factors of health workers in our Radiation Oncology Clinic.
METHODS: Thirty-six persons working at our clinic were included in the study. For determining the sociodemographic characteristics of the participants, a personal information form was designed. For data collection, Beck Depression Inventory (BDI) and Maslach Burnout Inventory were used.
RESULTS: According to BDI score results, moderate depression was detected in 1 person (2.8%). A significant correlation was detected between total Maslach score and BDI score. In our
study, a comparison of workers with and without chronic diseases revealed that differences in personal accomplishment (PA) points were significant (p=0.04) and in depersonalization (D) values were close to significant between the two groups. There was a significant difference (p=0.003) in PA between people that found their working conditions insufficient when compared with those who did not. A significant difference was
detected between personality and PA values.
CONCLUSION: Health workers in the Radiation Oncology Clinic have psychological difficulties, and more studies should be conducted in this area including a greater number of workers. By increasing the quality of life of health workers, productivity can also be increased.

OBJECTIVE: In this study, we aimed to examine patients with three port-laparoscopic cholecystectomy (LC) due to symptomatic cholelithiasis and to investigate the safety of the three-port LC, retrospectively.
METHODS: In total, 32 patients who received three port-LC due to symptomatic cholelithiasis were investigated in a retrospective fashion. Requirement of a fourth port, length of operation,
and complication rates were evaluated.
RESULTS: Twenty-four cases (75%) were female and 8 (25%) were male. Out of 32 patients, 29 (90.6%) received the threeport laparoscopic cholecystectomy successfully. Three (9.37%)
cases required a fourth port. None of the cases demonstrated mortality or major complications such as biliary fistula, leak, or injury.
CONCLUSION: Three-port LC in patients with symptomatic cholelithiasis was found to be safe and no increase in morbidity was observed.

OBJECTIVE: We aimed to investigate thyroid functions and to compare the thyroid hormone levels in healthy preterm and term infants.
METHODS: Thyroid stimulating hormone (TSH) and free thyroxine (FT4) levels determined in healthy term (≥37 gestational weeks) and preterm (<37 gestational weeks) neonates on the
postnatal third day were retrospectively evaluated. Infants whose mothers with thyroid disease, treated in neonatal intensive care unit for diseases including sepsis, respiratory distress, etc and <31 weeks preterms were excluded.
RESULTS: We studied 371 neonates (190 males, 51.2%; 181 females, 48.8%). There was no significant relationship among infant groups regarding TSH values (p>0.05). FT4 values were significantly higher in term infants than in preterm infants (p<0.05). There was a significant difference in FT4 values between term and preterm infants.
CONCLUSION: Hypothyroxinemia was detected more commonly in healthy preterm infants than in healthy term infants.

OBJECTIVE: Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. They are difficult to diagnose and challenging to treat. Treatment options for GBM have not changed over the years despite its high frequency in patients. This study was planned to examine the effects of treatment options on the duration of life in patients with GBM.
METHODS: In this study, we retrospectively evaluated 32 patients (16 male, 16 female) with a GBM diagnosis who were treated in the department of neurosurgery. All of the patients were informed about the disease and the treatment modalities. The Karnofsky performance scale was used to evaluate performance status and survival times were noted.
RESULTS: The median age was 64 years, the median follow–up duration was 7.5 months and the mean of performance status was 59.06±9.95.
CONCLUSION: The results of this study indicate that the performance status of patients diagnosed with GBM is in close relation to their initial prognosis.

Stevens-Johnson syndrome is a disease characterized by fever, purulent conjunctivitis, erosive stomatitis, and skin lesions with generalized exanthem. Many factors including drugs, infectious agents, carcinomas, leukemias, and collagen tissue diseases are known to play a role in its etiology. Radiotherapy is one of the factors that rarely has a part in the etiology of this disease. However, it is not clear whether radiotherapy is an etiological factor in and of itself. We present a case who had been receiving radiotherapy concurrently with docetaxel and cisplatin chemotherapy for epidermoid carcinoma. The patient developed erythema, bullae and occasional eroded areas that started at the site of radiation on the 34th day of radiotherapy and spread to the whole body, as well as hemorrhagic crusts and conjunctival hyperemia.

Sinonasal tract mucosal malignant melanomas are rare, accounting for between 0.3% and 2% of all malignant melanomas and about 4% of head and neck melanomas. They occur in older patients of both genders and frequently have poor prognoses. Surgery accompanied by radiation and/or chemotherapy is generally used as treatment. The frequency of local recurrence is high and recurrence is also the major determinant of treatment failure. Herein we report the case of a 76 year-old woman who was admitted with unilateral nasal obstruction and epistaxis. She also had a mass lesion in the sinonasal tract of her paranasal BT. A histological examination of the mass indicated malignant melanoma.

Pulmonary sequestration is a rare congenital malformation of lung. It is characterized by a nonfunctioning lung tissue originating from bronchopulmonary system that has anomalous systemic arterial blood supply. The two forms of pulmonary sequeastration are intrapulmonary, which is surrounded by normal lung tissue, and extrapulmonary, which has its own pleural investment. Radiologically, they may present as pneumonic infiltration, cystic nodules and rarely mass images. The patient was evaluated for solitary pulmonary nodule in our clinic and diagnosed as intralobar pulmonary sequestration. We decided to publish this case to remind that in the differential diagnosis of solitary pulmonary nodules pulmonary sequestration should be taken to highlight.

Descending necrotizing mediastinitis (DNM) is a rare fatal complication. It mostly develops due to severe oropharyngeal or odontogenic infections. A 50-year-old female patient who admitted to our department with the diagnosis of DNM underwent tracheotomy, and the abscess in her neck was drained with transcervical resection. Necrotic tissue in the area was debrided. Since thorax computerized tomography revealed formation of empyema pouches and emission of pus content from the retropharyngeal area into the mediastinum, decortication and empyemectomy were performed. The mediastinal pleura was resected and the mediastinum was cleaned. The patient was discharged with full recovery. Descending mediastinitis secondary to a deep neck infection is a rare occurrence. This study aims to share this successfully treated case in the light of the literature.

Heterotopic ossification is an entity characterized by a new bone formation in a tissue that is not normally ossified. In 1918, Dejerine and Ceillier defined ”paraosteoarthropathy” for the first time. Heterotopic ossification is a frequent complication after traumatic brain injury and also of spinal cord injuries. In general, trauma increases the heterotypic ossification incidence. Heterotopic ossification is usually observed in three groups as neurogenic heterotopic ossification, traumatic heterotopic
ossification and progressive myositis ossificance. Heterotopic ossification is usually seen in the large joints. Treatment options for heterotopic ossification are protection of joint range of motion, medication (anti-inflammatory drugs), radiotherapy, and surgical excision. Prophylaxis of heterotopic ossification is more important than treatment. Non-steroidal anti-inflammatory drugs, especially indomethacin, are used for prophylaxis. Surgical resection of heterotopic ossification can be applied after the completion of maturation. In patients at high risk for developing heterotopic ossification, prophylactic
radiotherapy is more effective than anti-inflammatory drugs.