Evaluation of the Relationship between Frailty and Fracture Risk using Fracture Risk Assessment Tool in Patients 65 Years and Over

Demiri�, Berkay; Basat, Sema; Kurt, Fatma; Aksakal, Berrin; Basat, Okcan

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Evaluation of the Relationship between Frailty and Fracture Risk using Fracture Risk Assessment Tool in Patients 65 Years and Over [South Clin Ist Euras]

South Clin Ist Euras. 2023; 34(1): 42-48 | DOI: 10.14744/scie.2022.66564

Evaluation of the Relationship between Frailty and Fracture Risk using Fracture Risk Assessment Tool in Patients 65 Years and Over

Berkay Demiri�¹, Sema Basat¹, Fatma Kurt¹, Berrin Aksakal¹, Okcan Basat²
¹Department of Internal Medicine, University of Health Sciences, �mraniye Training and Research Hospital, �stanbul, T�rkiye
²Department of Family Medicine, University of Health Sciences, Gaziosmanpa�a Training and Research Hospital, �stanbul, T�rkiye

INTRODUCTION: There is no information in the literature examining the relationship between frailty and fracture risk. Our study used the fracture risk assessment tool (FRAX) to assess the link between frailty and fracture risk.
METHODS: A single-center cross-sectional study. There were 120 patients overall who were 65 years of age or older. We assessed each patient�s frailty using the Canadian Health and ag-ing study (CHAS) Criteria. By using the FRAX, these patients� fracture risks were identified (FRAX). Measurements were made of the amounts of albumin, parathormone, 25-hydrox-yvitamin D, calcium, and plasma.
RESULTS: Forty-two men and 78 women out of 120 patients were evaluated. Frailty and FRAX showed a substantial positive connection (p=0.01). Frailty risk was 1.228 times greater (p=0.023) in the group with a high risk of hip fracture. The risk of frailty was 2,755 times higher in the group, which is a high risk for significant osteoporotic fracture risk (p=0.027).
DISCUSSION AND CONCLUSION: There is a positive relationship between frailty and risk of fracture evaluated by FRAX in individuals aged 65 years or older. Hip fracture risk and significant osteoporotic fracture risk both rise with increasing frailty.

Keywords: Elderly, fracture risk assessment tool; frailty; osteoporosis

65 Ya� ve �zeri Hastalarda K�r�lganl�k ve K�r�k Riski Aras�ndaki �li�kinin Frax Kullan�larak De�erlendirilmesi

Berkay Demiri�¹, Sema Basat¹, Fatma Kurt¹, Berrin Aksakal¹, Okcan Basat²
¹Sa�l�k Bilimleri �niversitesi, �mraniye E�itim Ve Ara�t�rma Hastanesi, �� Hastal�klar� Klini�i
²Sa�l�k Bilimleri �niversitesi, Gaziosmanpa�a E�itim Ve Ara�t�rma Hastanesi, Aile Hekimli�i

G�R�� ve AMA�: Literat�rde k�r�k riski ile k�r�lganl�k aras�ndaki ili�kiyi de�erlendiren veri bulunmamaktad�r. �al��mam�zda FRAX ad� verilen K�r�k Riski De�erlendirme Arac� ile k�r�lganl�k ve k�r�k riski aras�ndaki ili�kinin de�erlendirilmesi ama�lanm��t�r.
Y�NTEM ve GERE�LER: Tek merkezli kesitsel bir �al��mad�r. �al��maya 65 ya� ve �zeri toplam 120 hasta dahil edildi. T�m hastalara k�r�lganl�k-lar�n� belirlemek i�in Kanada Sa�l�k ve Ya�lanma �al��mas� (CHAS) Kriterleri uyguland�. Bu hastalar�n k�r�k riskleri, K�r�k Riski De�erlendirme Arac� (FRAX) uygulanarak tespit edildi. Plazma kalsiyum, 25-hidroksi D vitamini, alb�min ve parathormon d�zeyleri �l��ld�.
BULGULAR: Y�z yirmi hastan�n 78�i kad�n (%65) ve 42�si erkek (%35) olarak de�erlendirildi. K�r�lganl�k ile FRAX aras�nda pozitif y�nde anlaml� korelasyon saptand� (p<0.01). Kal�a k�r�� riski y�ksek olan grupta k�r�lganl�k riski 1.228 kat daha y�ksekti (p=0.023). Maj�r osteoporotik k�r�k riski a��s�ndan y�ksek risk alt�nda olan grupta k�r�lganl�k riski 2,755 kat daha y�ksekti (p=0.027).
TARTI�MA ve SONU�: Altm�� be� ya� ve �zeri bireylerde k�r�lganl�k ile FRAX ile de�erlendirilen k�r�k riski aras�nda pozitif bir ili�ki vard�r. K�r�lganl�k artt�k�a maj�r osteoporotik k�r�k riski ve kal�a k�r�� riski de artmaktad�r.

Anahtar Kelimeler: FRAX, k�r�lganl�k; osteoporoz; ya�l�l�k.

Berkay Demiri�, Sema Basat, Fatma Kurt, Berrin Aksakal, Okcan Basat. Evaluation of the Relationship between Frailty and Fracture Risk using Fracture Risk Assessment Tool in Patients 65 Years and Over. South Clin Ist Euras. 2023; 34(1): 42-48

Corresponding Author: Berrin Aksakal, T�rkiye
Manuscript Language: English

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