South Clin Ist Euras. 2020; 31(1): 69-73 | DOI: 10.14744/scie.2020.00921

COVID-19 and Pregnancy

Hale Ankara Aktaþ, Yasmin Aboalhasan, Taylan Aygün, Gülfem Baþol, Ahmet Kale
Department Of Gynecology And Obstetrics, Kartal Dr. Lütfi Kýrdar City Hospital,lstanbul,turkey

Objective: The aim of this study is to evaluate the clinical findings of Coronavirus Disease 2019 (COVID-19) developed during pregnancy
and to summarize the perinatal, postnatal, and neonatal outcomes.

Methods: A period between February 1, 2020 and May 25, 2020, using the databases of Pubmed, MedRxiv and Google Scholar, a comprehensive
literature survey has been conducted covering the period. When searching, “COVID-19, pregnancy, maternal infection, fetal
infection, maternal mortality, fetal mortality, vertical transmission, complications, clinical findings, SARS-CoV-2” keywords have been used.
No language restrictions have been applied to scan as much data as possible.

Results: Between February 1, 2020 and May 25, 2020, nineteen papers reporting data from 168 pregnancies were included in this study.
Most of the articles cover pregnant women in the third trimester. On initial application to hospital, fever was detected in 70% of cases and
cough in 34%. Lymphocytopenia was observed in 55% of cases and C-reactive protein elevation was observed in 65%. It was found that
77% of women gave birth by caesarean section. Four patients were taken to the intensive care unit, but no maternal deaths were seen. One
neonatal death and one intrauterine death have also been reported.

Conclusion: It has been observed that COVID-19 virus does not cause an adverse situation on pregnant women and newborns in the early
stages. With all the precautions taken and the applications made, both health workers and the mother and fetus were able to complete the
process without being adversely affected by this virus. It will be useful to follow up long-term results

Keywords: COVID-19, fetal infection; maternal infection; pregnancy; SARS-CoV-2; vertical transmission.

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COVID-19 ve Gebelik

Hale Ankara Aktaþ, Yasmin Aboalhasan, Taylan Aygün, Gülfem Baþol, Ahmet Kale
Kartal Dr. Lütfi Kýrdar Þehir Hastanesi, Kadýn Hastalýklarý ve Doðum Kliniði, Ýstanbul

Amaç: Bu çalýþmanýn amacý, gebelik sýrasýnda geliþen “Coronavirus Disease 2019 (COVID-
19)”un klinik bulgularýný deðerlendirmek, perinatal, postnatal ve neonatal sonuçlarýný özetlemektir.

Gereç ve Yöntem: Çalýþmada, Pubmed, MedRxiv ve Google Scholar veri tabanlarýný kullanarak
1 Þubat 2020 ile 25 Mayýs 2020 tarihleri arasýndaki dönemi kapsayan kapsamlý bir
literatür araþtýrmasý yapýldý. Arama yaparken “COVID-19, gebelik, maternal enfeksiyon, fetal
enfeksiyon, maternal mortalite, fetal mortalite, vertikal bulaþ, komplikasyonlar, klinik bulgular,
SARS-CoV-2” anahtar kelimeleri kullanýldý. Mümkün olduðunca çok verinin taranmasý için
herhangi bir dil kýsýtlamasý uygulanmadý.

Bulgular: Bu çalýþmaya, 1 Þubat 2020 ile 25 Mayýs 2020 tarihleri arasýnda, 168 gebelikten
veri bildiren 19 makale dahil edilmiþtir. Makalelerin çoðu, üçüncü trimesterdeki gebeleri kapsamaktadýr.
Hastaneye ilk baþvuruda, olgularýn %70’inde ateþ, %34’ünde öksürük tespit edilmiþtir.
Olgularýn %55’inde lenfositopeni, %65’inde C-reaktif protein yüksekliði gözlenmiþtir.
Kadýnlarýn %77’sinin sezaryen ile doðum yaptýðý tespit edilmiþtir. Dört hasta yoðun bakým
ünitesine alýnmýþ, ancak maternal ölüm görülmemiþtir. Bir yenidoðan ölümü ve bir intrauterin
ölüm de bildirilmiþtir.

Sonuç: COVID-19 virüsünün gebeler ve yenidoðan üzerinde erken dönemde olumsuz bir
duruma yol açmadýðý gözlenmiþtir. Alýnan tüm önlemler ve yapýlan uygulamalar ile hem saðlýk
çalýþanlarý hem anne hem de fetüs bu virüsten olumsuz etkilenmeden süreci tamamlayabilmiþtir.
Uzun dönem sonuçlarýnýn takip edilmesinde fayda olacaktýr.

Anahtar Kelimeler: COVID-19, fetal enfeksiyon; gebelik; maternal enfeksiyon; SARS-CoV-2; vertikal bulaþ.

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