Two Cases of Breast Cancer Presenting Primarily with Skin Metastasis

Cutaneous metastases represent 2% of all metastases. Although rare in clinical practice, cutaneous metastases are important in that they indicate a poor prognosis for the disease. Cutaneous metastases are usually symptoms of advanced internal malignancies, and rarely, they may be the first clinical manifestation of an unknown internal neoplasm. Here we report 2 previously undiagnosed patients who presented at a dermatology outpatient clinic with firm, ulcerated lesions on the skin as the first sign of breast carcinoma. Skin metastases of internal malignancies should be considered in the differential diagnosis in cases with atypical nodules on the skin.

Deri Metastazlarý Ýle Bulgu Veren Ýki Meme Kanseri Olgusu

Kutanöz metastazlar tüm metastazlarýn yaklaþýk %2’sini oluþtururlar. Klinikte oldukça nadir olarak görülseler de hastalýkta kötü prognoz göstergesi olmalarý kutanöz metastazlara önem kazandýrýr. Kutanöz metastazlar genellikle ilerlemiþ kanserlerin bulgusu olmakla beraber nadiren tanýsý konmamýþ internal malignitenin ilk bulgusu olabilirler. Burada, daha önce taný almamýþ, ilk bulgu olarak meme derisinde sertlik ve yara þikayetiyle dermatoloji polikliniðine baþvuran ve meme kanseri tanýsý konan iki olgu sunuldu. Deride atipik lezyonlarla baþvuran hastalarda iç organ malignitelerinin metastazlarý da akýlda tutulmalýdýr.