South Clin Ist Euras. 2021; 32(4): 376-380 | DOI: 10.14744/scie.2021.25991

Tip 2 Diabetes Mellitus Tanýlý Geriatrik Hastalarda D Vitamini Düzeyi ile Kardiyovasküler Risk Skorlarý Arasýndaki Ýliþki

Damla Ortaboz¹, Sema Basat¹, Ridvan Sivritepe^2
1Saðlýk Bilimleri Üniversitesi Ümraniye Eðitim ve Araþtýrma Hastanesi, Ýç Hastalýklarý Kliniði, Ýstanbul
²Ýstanbul Medipol Üniversitesi Týp Fakültesi Pendik Hastanesi, Ýç Hastalýklarý Anabilim Dalý

GÝRÝÞ ve AMAÇ: Bu çalýþmanýn amacý, geriatrik diyabetik hastalarda vitamin D düzeyi ile QRISK2, BNF, ASSING, SCORE ve Framingham gibi çeþitli kardiyovasküler risk skorlama sistemleri arasýndaki iliþkiyi deðerlendirmektir.
YÖNTEM ve GEREÇLER: Çalýþmaya D vitamini yetersizliði olan 60 diyabetik geriatrik hasta (10–30 ng/mL) ve D vitamini eksikliði olan 40 geriatrik hasta (<10 ng/mL) dahil edildi. Hastalarýn QRISK2, BNF, ASSIGN, SCORE ve Framingham gibi kardiyovasküler hastalýk riskini gösteren skorlarý hesaplandý. Tüm deðerler bu iki grup arasýnda karþýlaþtýrýldý.
BULGULAR: D vitamini eksikliði olan hastalarda Framingham risk skoru (p<0.001), BNF (p=0.001) ve SCORE (p<0.001) anlamlý olarak yüksek iken diðer skorlarda gruplar arasý anlamlý farklýlýk yoktu. D vitamini düzeyi ile Framingham risk skoru (p<0.001 r=-0.384), BNF skoru (p=0.003
r=-0.299) ve SCORE skoru (p=<0.001 r=-0.407) arasýnda zayýf fakat istatistiksel olarak anlamlý negatif bir korelasyon vardý.
TARTIÞMA ve SONUÇ: Bu çalýþmada, diyabetik geriatrik hastalarda Framingham, BNF ve ASSIGN gibi kardiyovasküler risk skoru ile serum D vitamini konsantrasyonu arasýnda yakýn bir iliþki bulduk.

Anahtar Kelimeler: BNF Skoru, Framingham Risk Skoru; geriatri; kardiyovasküler risk skorlarý; Tip II Diabetes Mellitus; vitamin D eksikliði.

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The Relationship Between Vitamin D Levels and Cardiovascular Risk Scores in Geriatric Patients with Type 2 Diabetes Mellitus

Damla Ortaboz¹, Sema Basat¹, Ridvan Sivritepe^2
1Department of Internal Medicine, University of Health Sciences Ümraniye Training and Research Hospital, Ýstanbul, Turkey
²Department of Internal Medicine, Ýstanbul Medipol University Faculty of Medicine Pendik Hospital, Ýstanbul, Turkey

INTRODUCTION: The aim of this study is to evaluate the relationship between vitamin D levels and various cardiovascular risk scoring systems such as QRISK2, BNF, ASSING, SCORE and Framingham in geriatric diabetic patients.
METHODS: 60 diabetic geriatric patients with vitamin D deficiency (10–30 ng/mL) and 40 geriatric patients with vitamin D deficiency (<10 ng/mL) were included in the study. The scores of the patients indicating cardiovascular disease risks such as QRISK2, BNF, ASSIGN, SCORE and Framingham were calculated. All values were compared between these two groups.
RESULTS: While the Framingham risk score (p<0.001), BNF (p=0.001) and SCORE (p<0.001) were found to be significantly higher in patients with vitamin D deficiency, other scores did not significantly differ between the groups. There was a weak but statistically significant negative correlation between 25[OH] D levels with Framingham risk score (p<0.001 r=-0.384), BNF score (p=0.003 r=-0.299), and Score score (p <0.001 r=-0.407).
DISCUSSION AND CONCLUSION: In the present study, we found a close relationship between the Framingham, BNF and ASSIGN cardiovascular risk score and serum vitamin D concentrations in diabetic geriatric patients.

Keywords: BNF Score, Framingham Risk Score; geriatric; risk scores; Type II Diabetes Mellitus, various cardiovascular; vitamin D deficiency.

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